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-synuclein, which is a principal part of Lewy bodies, in PARK 1 in 1997 and parkin in PARK two in 1998, which is an E3 ubiquitin ligase and results in endoplasmic reticulum (ER) tension, suggest that dysfunction of your intracellular proteinase devices, which include ubiquitin-proteasome program or lysosomal technique, which removes pointless poiso
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